Extramedullary hematopoiesis in β-thalassemia major patient: a case report and review of the literature

Extramedullary hematopoiesis (EMH), as a compensatory phenomenon, refers to the blood cell formation outside of bone marrow that occurs once cells in circulatory system fail meet individuals’ needs. EMH is rare moderate severe beta thalassemia because most symptomatic patients are effectively managed with transfusion. However, receive transfusions like β-thalassemia intermedia (β-TI) indicated at increased risk for developing EMH. This paper describes case 15-year-old female adolescent major (β-TM), suffering from form affecting sinus cavities, characterized by headache, sinusitis, and nasal obstruction, confirmed physical-pathological examinations computerized tomography (CT) scan findings. The this patient could be significantly attributed lack regular recent years. It was concluded β-TM along occurrence cavities had led complex case, carrying heavy burden disease patient.